Dr Jeffrey Tu

 

MBBS (University of Sydney) · FRACP (Gastroenterology) · Specialist Gastroenterologist & Hepatologist
Conjoint Lecturer, UNSW · AHPRA Registration No. MED0001186651

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Dr Jeffrey Tu is a Sydney-based specialist gastroenterologist and hepatologist with more than two decades in clinical medicine, sixteen of those years in private practice on Sydney’s Lower North Shore. He graduated from the University of Sydney in 2002 and obtained his Fellowship of the Royal Australasian College of Physicians (FRACP) in Gastroenterology in 2010. In 2010 he completed a fellowship in advanced interventional endoscopy and ERCP at the Prince of Wales Hospital, Randwick.

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After obtaining his FRACP, Dr Tu spent a further year in Melbourne training at the Centre for GI Health and Monash University, developing expertise in neurogastroenterology with manometry training.

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He consults from The Mater Hospital (Wollstonecraft), East Sydney Private Hospital, Northern Beaches Hospital (Frenchs Forest), Freshwater Day Hospital, and the Centre for Digestive Diseases in Five Dock, and performs gastroscopy and colonoscopy at each of these accredited centres.

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A CLINICAL FOCUS ON FUNCTIONAL GUT DISORDERS

Dr Tu’s primary interest is the patient with persistent bloating, constipation or diarrhoea who has been told everything is normal. Their endoscopy and colonoscopy are clear, laxatives haven’t worked, and a low-FODMAP diet hasn’t helped. These are the patients he actively seeks out.

His approach combines two complementary lines of investigation:

• Neuromotility assessment. Dr Tu personally interprets anorectal and gastrointestinal manometry and intestinal transit studies, to establish how the gut is actually moving rather than assuming.

• Microbiome assessment. Testing for small intestinal bacterial overgrowth (SIBO) and detailed microbiome analysis show what is happening inside the gut.

Read together, motility and microbiome findings often explain symptoms that neither test can explain alone, and they point to a specific, targeted treatment plan in place of trial and error.

His clinical interests span luminal gastroenterology and hepatology: irritable bowel syndrome and disorders of gut–brain interaction, chronic constipation and motility disorders, SIBO, inflammatory bowel disease (Crohn’s disease and ulcerative colitis), refractory Helicobacter pylori, parasitic gastrointestinal infections (Blastocystis hominis, Dientamoeba fragilis, Giardia), reflux and Barrett’s oesophagus, coeliac disease, fatty liver disease (MASLD), viral hepatitis, and bowel cancer screening and surveillance.

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SAFE, HIGH-QUALITY ENDOSCOPY

Where endoscopy is needed, Dr Tu holds it to a measurable standard. He regularly audits his own adenoma detection rate (ADR) and colonoscopy completion rate, because quality in endoscopy should be measured rather than assumed.

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MICROBIOME MEDICINE AND FMT

Beyond standard gastroenterology, Dr Tu offers faecal microbiota transplantation (FMT), microbiome-based treatments, and trans-colonic antibiotic infusion for resistant intestinal parasitic infections.

He is a Visiting Medical Officer at the Centre for Digestive Diseases, founded by the late Professor Thomas Borody (1950–2025). Dr Tu trained directly under Professor Borody and has extensive experience in FMT and microbiome therapeutics.

He speaks fluent Mandarin and welcomes patients from Sydney’s Chinese-speaking communities, as well as international referrals from Taiwan, Singapore, and the broader Asia-Pacific region.

RESEARCH AND PUBLICATIONS

Dr Tu’s peer-reviewed and presented research includes:

1. Vonoprazan-based regimens for refractory Helicobacter pylori. Gunaratne AW, Hamblin H, Clancy A, Tu J, et al. Combinations of antibiotics and vonoprazan for the treatment of Helicobacter pylori infections — Exploratory study. Helicobacter. 2021;26(5):e12830. PubMed: https://pubmed.ncbi.nlm.nih.gov/34247436/ Full text (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC8518953/ DOI: https://doi.org/10.1111/hel.12830

2. Triple antibiotic therapy and faecal calprotectin in ulcerative colitis. Tu J, et al. Does Triple Antibiotic Therapy Reduce Faecal Calprotectin Levels and Gastrointestinal Symptoms in Patients With Ulcerative Colitis? A Retrospective Study. Presented at Digestive Disease Week (DDW), 2019. Abstract 2930.

3. Antibiotic infusion for symptomatic Blastocystis hominis and Dientamoeba fragilis infections. Tu J, et al. A Retrospective Review of Antibiotic Infusion for Symptomatic Parasitic Infections. Presented at the American College of Gastroenterology (ACG) Annual Scientific Meeting, 2018. Abstract S2091.

4. Occult hepatitis B in pregnancy — implications for antenatal screening. Chang P, Tu J, et al. Development of occult hepatitis B viral infection in pregnancy: implications for antenatal screening in women from endemic areas. Obstetric Medicine. 2010;3(3):115–118. Full text (PMC): https://pmc.ncbi.nlm.nih.gov/articles/PMC4989587/ DOI: https://doi.org/10.1258/om.2010.090057

 

QUALIFICATIONS AT A GLANCE

• Medical Degree: MBBS, University of Sydney (2002)

• Academic Appointment: Conjoint Lecturer, UNSW

• Specialist Fellowship: FRACP in Gastroenterology, Royal Australasian College of Physicians (2010)

• Advanced Training: Advanced Interventional Endoscopy and ERCP, Prince of Wales Hospital, Sydney (2010)

• Advanced Training: Neurogastroenterology and Manometry, Centre for GI Health and Monash University, Melbourne (2011)

• Advanced Training: Microbiome Medicine and FMT, under Prof Thomas Borody, Centre for Digestive Diseases

• Professional Membership: Gastroenterological Society of Australia (GESA)

• Languages: English, Mandarin

• Hospital Appointments: The Mater Hospital (Wollstonecraft) · East Sydney Private Hospital · Northern Beaches Hospital · Freshwater Day Hospital · Centre for Digestive Diseases (Five Dock)